The home side got off to a fast start, kicking the first three goals of the game on the way to a 31-point quarter-time lead.
Freo continued to apply the pressure in the second term to go into the main break with the advantage.
David Mundy has 10 possessions and two goals from the midfield.
Hayden Ballantyne's defensive intensity and workrate in the forward half has been excellent, helping him to kick three goals.
Fremantle 9.8 (62) leads Melbourne 3.5 (23)
